@deidre77 Thank you and my apologies for delay but just seeing this now. I had a radical cystectomy done robotically at Mount Sinai in NY in January 24 with a urostomy. No issues with the surgery or life with the bag. Minimally invasive with 6 small incisions, discharged after 4 days with Tylenol! I’m still amazed. Unfortunately the pathology showed it was stage 3, not stage 2 which was the original thought post TURBT at the local community hospital I started at in NJ. 6 cycles of chemo (gemcitibine and cisplatin); cancer was not detectable based on Signatera after cycle 4. I won’t kid you, chemo was not easy with the usual side effects (nausea, diarrhea and some loss of appetite) plus I developed blood clots in minor veins in my arms. The cancer became detectable again almost a year later in May 2025 and I had 6 cycles of Padcev and Keytruda. Treatment sessions were much easier but bad skin rashes, complete loss of appetite and sense of taste were very hard. The cancer became non detectable based on PET scan and Signatera after cycle 4. The plan would have been to stay on Padcev and Keytruda until it stopped working or until my body couldn’t tolerate it. That happened in Oct 2025. I had lost about 35 pounds and became very weak. My doctor stopped treatment until December 2025. I’m now only on Keytruda with far fewer side effects, eating and sleeping well and maintaining my weight. I’ve just been discharged from Physical Therapy and am getting back to my routine at the gym and life in general. Scans and Signatera remain good . It was very hard when the cancer returned in May 2025 but I’ve learned that this journey isn’t always a straight line and am very blessed to have phenomenal family friends, doctors and medical professionals guiding my care. It gives me great peace of mind. I don’t like to think about what would have happened if I had not listened to my sister and not gone to Mount Sinai for a second opinion. The medical team is truly awesome and I think of my 3 main drs as honorary sons ( that I didn’t have to put through medical school😉)