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Has anyone experienced 'Airway Remodelling'?

MAC & Bronchiectasis | Last Active: 2 days ago | Replies (27)

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@sueinmn
Thank you so much for that, Sue. I am worried that it is something other than the 'normal' bronchiectasis remodelling.

My test results are coming in slowly. So far mild Neutropenia, have C3C biomarker for intestital remodelling in fibrotic disease; C4 is low (which is protein for immune system function). My GP says that there is something going on in my immune system. My sinus HRCT was unremarkable acc to my GP (haven't had second specialist appt yet); lung HRCT report not back yet; sputums ok.

"The C3C biomarker assay measures specific neo-epitope fragments of type III collagen generated through cathepsin-mediated degradation, serving as an indicator of interstitial matrix remodeling in fibrotic diseases."

I have GERD and reflux. My naturopath recently picked up Mast Cell Activation, Klebsiella pneumonia, Coronavirus (which she says 70% of her clients have), Aspergillus niger and round worm (via electro dermal testing - not recognised generally by Western med). I had Coronavirus in 2022 and this is the first time back to naturopath since...so maybe residual in my system? The Aspergillus I am wondering if I picked it up last year in Qld, and I don't know about the Klebsiella.

The severe SOB I am experiencing (not all the time, but intermitently) started on my trip to Qld last year after I camped alongside a sugarcane factory burning off great funnels of black and white smoke...and it then continued on my travels and I seemed to be reacting to everything - smoke, dust, damp etc...which makes sense with a Mast Cell Activation.

I am trying to piece it together. The specialist seemed alarmed that there had been such a drop in lung function.

I have tried to sumarise my Spirometry results over the years (attached) and would be very grateful for any light you or anyone could throw on them for me.

Thank you so much!

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Replies to "@sueinmn Thank you so much for that, Sue. I am worried that it is something other..."

@narelled23 I'm not a doctor, so I don't try to interpret test results, even my own.
It does sound like something besides bronchiectasis is going on - I have friends with idiopathic pulmonary fibrosis (IPF) and interstitial lung disease (ILD) diagnoses in addition to bronchiectasis - perhaps that is where all of your testing is leading the doctors.
Are you in the care of a good pulmonary specialist? This looks to be way beyond the scope of either a naturopath or general practitioner.

PS Even as a strong supporter of complementary and alternative medicine, I have huge skepticism about dermal testing for diagnosis of infections. Any single machine or test that purported to diagnose a wide range of maladies has always been proven by science to be wrong.