Bone Health Trestment

Posted by jwmusic65 @jwmusic65, Feb 13 2:47pm

Looking for otc possibilities during breast cancer treatment. I am currently on Anastrozole. Looking at an otc supplement called AlgaeCal. Am open to suggestions. This supplement is directed toward bone health.

Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.

AlgaeCal has been discussed many times here. If you use the search box, you'll get a lot of information thag may be helpful.

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I purchased Algecal through Amazon and then their website. They have a great support team you can call. Taking on recommendations from my Rheumatologist. I hope you recover well.

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Strontium citrate is a good supplement also. IT is somewhere between a medicine and a supplement. Basically, it is a supplement that is used as a medicine.
Strontium has placed in the top similar to Forteo and Prolia for building bone quality.

See photos provided below with some links to the research.

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Profile picture for mcchesney @kathleen1314

Strontium citrate is a good supplement also. IT is somewhere between a medicine and a supplement. Basically, it is a supplement that is used as a medicine.
Strontium has placed in the top similar to Forteo and Prolia for building bone quality.

See photos provided below with some links to the research.

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@kathleen1314 I clicked on the images and saved them to zoom in see if I could read them and it is blurry and unreadable. Any way you can share these so we can see the data or a link to where you got these images? Thanks!

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Profile picture for loplady @loplady

@kathleen1314 I clicked on the images and saved them to zoom in see if I could read them and it is blurry and unreadable. Any way you can share these so we can see the data or a link to where you got these images? Thanks!

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@loplady
Thank you, amazing how some photos just don't work isn't it?

The links were on the photos, but here the hot links are:
Bone Biopsies and research for strontium biopsies:
https://onlinelibrary.wiley.com/doi/10.1359/jbmr.071012
Here is a post which I did on the TBS study with the research hot linked:
https://www.inspire.com/groups/bone-health-and-osteoporosis/discussion/tbs-dexa-and-strontium/

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Profile picture for mcchesney @kathleen1314

@loplady
Thank you, amazing how some photos just don't work isn't it?

The links were on the photos, but here the hot links are:
Bone Biopsies and research for strontium biopsies:
https://onlinelibrary.wiley.com/doi/10.1359/jbmr.071012
Here is a post which I did on the TBS study with the research hot linked:
https://www.inspire.com/groups/bone-health-and-osteoporosis/discussion/tbs-dexa-and-strontium/

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@kathleen1314 The study you linked is for strontium ranelate, not strontium citrate. Do you have a link to a similar study for strontium citrate? Much appreciated!

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Well, all studies on bone health in terms of strontium is on all strontium,

To speak to strontium via ranelate in particular though, none of the additives in strontium ranelate are tied to bone health so bone research on strontium ranelate is research on all strontium.

But if you are looking at a possible reaction, then you need to look at additives like ranelate also, but if you are looking for bone health then any strontium research on bone health will give you the information which you need , which is the case with strontium ranelate.

But most studies do not take calcium out of a person's diet or other supplements so although calcium is a bone builder it is not considered something to negate the results of a strontium study nor are supplements like melatonin. Nothing can be completely pure in studying health and supplements or medicines because you are studying people and their lives and supplements can be varied. This is one reason scientists like a varied layered approach, animal studies, population studies and studies with as pure a supplement narrowing as possible. which all of these studies are, including the strontium via ranelate studies.

Here is an example of this scientific research metality; a research compilation of lots of strontium research, not labeling one ranelate or another citrate just an overview of strontium, how it acts and why it acts:
https://www.sciencedirect.com/science/article/pii/S2352187220300334
But yes I have strontium citrate studies:
Mots, Comb studies compared on Boneladies' excellent blog; these two are considered strontum citrate studies but other bone builders were included:
https://strontiumforbones.blogspot.com/2017/02/mots-and-comb-study-comparison.html
Mirza study:
https://pdfs.semanticscholar.org/bdce/ac5e3fae890f6dd1902cb45734b96433b165.pdf
3 case studies by Dr. Sara Dehart:
https://strontiumforbones.blogspot.com/2018/01/in-memory-of-sara-shackleford-dehart.html
For a supplement that is alot of studies!

AlgaeCal has several strontium citrate studies also but many of them also include calcium etc. which are bone builders.
https://www.ncbi.nlm.nih.gov/pubmed/21492428
https://www.ncbi.nlm.nih.gov/pubmed/26885697
Strontium Citrate Rabbit studies:
https://pubmed.ncbi.nlm.nih.gov/28485552/
An article with a historical overview of strontium, including a Mayo clinic investigation.Plus, this overview also highlights that all strontium research is considered bone health research unless nullified by the addition of an unusual bone additive other than strontium:
https://worldhealth.net/news/strontium_breakthrough_against_osteoporo/

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Profile picture for mcchesney @kathleen1314

Well, all studies on bone health in terms of strontium is on all strontium,

To speak to strontium via ranelate in particular though, none of the additives in strontium ranelate are tied to bone health so bone research on strontium ranelate is research on all strontium.

But if you are looking at a possible reaction, then you need to look at additives like ranelate also, but if you are looking for bone health then any strontium research on bone health will give you the information which you need , which is the case with strontium ranelate.

But most studies do not take calcium out of a person's diet or other supplements so although calcium is a bone builder it is not considered something to negate the results of a strontium study nor are supplements like melatonin. Nothing can be completely pure in studying health and supplements or medicines because you are studying people and their lives and supplements can be varied. This is one reason scientists like a varied layered approach, animal studies, population studies and studies with as pure a supplement narrowing as possible. which all of these studies are, including the strontium via ranelate studies.

Here is an example of this scientific research metality; a research compilation of lots of strontium research, not labeling one ranelate or another citrate just an overview of strontium, how it acts and why it acts:
https://www.sciencedirect.com/science/article/pii/S2352187220300334
But yes I have strontium citrate studies:
Mots, Comb studies compared on Boneladies' excellent blog; these two are considered strontum citrate studies but other bone builders were included:
https://strontiumforbones.blogspot.com/2017/02/mots-and-comb-study-comparison.html
Mirza study:
https://pdfs.semanticscholar.org/bdce/ac5e3fae890f6dd1902cb45734b96433b165.pdf
3 case studies by Dr. Sara Dehart:
https://strontiumforbones.blogspot.com/2018/01/in-memory-of-sara-shackleford-dehart.html
For a supplement that is alot of studies!

AlgaeCal has several strontium citrate studies also but many of them also include calcium etc. which are bone builders.
https://www.ncbi.nlm.nih.gov/pubmed/21492428
https://www.ncbi.nlm.nih.gov/pubmed/26885697
Strontium Citrate Rabbit studies:
https://pubmed.ncbi.nlm.nih.gov/28485552/
An article with a historical overview of strontium, including a Mayo clinic investigation.Plus, this overview also highlights that all strontium research is considered bone health research unless nullified by the addition of an unusual bone additive other than strontium:
https://worldhealth.net/news/strontium_breakthrough_against_osteoporo/

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@kathleen1314 Thanks for the links. Bottom line is that there are no peer reviewed, phase 3, double blinded, controlled studies on strontium citrate to reduce fracture risk. At best, it remains a supplement that may help but is not FDA approved for the treatment of osteoporosis. Perhaps one day it will be studied in this nature but doubt it will be because there is no ROI for drug or supplement companies.

I understand why some people take it, though, in the hopes it will help increase their BMD and thus reduce their fracture risk. There does seem to be some evidence for this in animal studies.

It’s an interesting supplement. I have considered taking it at times but have been hesistant due to the effect on DEXA and the lack of scientific research on strontium citrate for fracture reduction. This is the gold standard for me, having experienced an osteoporosis-related fracture in the past. My BMD has been quite stable over the years and not that low so I don’t put too much weight on it for my treatment.

Unfortunately, one cannot extrapolate studies on strontium ranelate to strontium citrate. Two chemical compounds carrying the same atom will not always have the same level of absorption or outcome in our bodies. An example of this would be thinking that sodium chloride and sodium bicarbonate have the same effect in our bodies because they both carry a sodium atom.

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Profile picture for oopsiedaisy @oopsiedaisy

@kathleen1314 Thanks for the links. Bottom line is that there are no peer reviewed, phase 3, double blinded, controlled studies on strontium citrate to reduce fracture risk. At best, it remains a supplement that may help but is not FDA approved for the treatment of osteoporosis. Perhaps one day it will be studied in this nature but doubt it will be because there is no ROI for drug or supplement companies.

I understand why some people take it, though, in the hopes it will help increase their BMD and thus reduce their fracture risk. There does seem to be some evidence for this in animal studies.

It’s an interesting supplement. I have considered taking it at times but have been hesistant due to the effect on DEXA and the lack of scientific research on strontium citrate for fracture reduction. This is the gold standard for me, having experienced an osteoporosis-related fracture in the past. My BMD has been quite stable over the years and not that low so I don’t put too much weight on it for my treatment.

Unfortunately, one cannot extrapolate studies on strontium ranelate to strontium citrate. Two chemical compounds carrying the same atom will not always have the same level of absorption or outcome in our bodies. An example of this would be thinking that sodium chloride and sodium bicarbonate have the same effect in our bodies because they both carry a sodium atom.

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@oopsiedaisy Thank you for sharing your research. May I ask you what treatment you use for your bone health?

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Profile picture for broken13 @broken13

@oopsiedaisy Thank you for sharing your research. May I ask you what treatment you use for your bone health?

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@broken13 I'm currently on Evenity. I have two more shots to go. Previously did 5+ years on Fosamax followed up by 5 months of Tymlos and 2 months of generic Forteo.

Also on bHRT for many years now and all the recommended lifestyle changes (diet/exercise). I take vitamin K. I'm no longer taking supplemental calcium but ensure I get 1000 mg in my diet every day. The latter is at my endocrinologist's recommendation. I have high urinary calcium.

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