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Has anyone experienced 'Airway Remodelling'?

MAC & Bronchiectasis | Last Active: 2 days ago | Replies (27)

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Profile picture for scoop @scoop

My understanding is that remodeling of airways is what happens in bronchiectasis. Affected breathing tubes become dilated (larger) allowing mucus to pool and natural clearance impossible.

Have they ruled out GERD/reflux? Aspergillosis? Do steroids help with the excess mucus?

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Replies to "My understanding is that remodeling of airways is what happens in bronchiectasis. Affected breathing tubes become..."

@scoop
am getting the impression that this is different, but not sure...my test results are coming in slowly. So far mild Neutropenia, have C3C biomarker for intestital remodelling in fibrotic disease; C4 is low (which is protein for immune system function). My GP says that there is something going on in my immune system. My sinus HRCT was unremarkable acc to my GP (haven't had second specialist appt yet); lung HRCT report not back yet; sputums ok.

"The C3C biomarker assay measures specific neo-epitope fragments of type III collagen generated through cathepsin-mediated degradation, serving as an indicator of interstitial matrix remodeling in fibrotic diseases."

I have GERD and reflux. My naturopath recently picked up Mast Cell Activation, Klebsiella pneumonia, Coronavirus (which she says 70% of her clients have), Aspergillus niger and round worm (via electro dermal testing - not recognised generally by Western med). I had Coronavirus in 2022 and this is the first time back to naturopath since...so maybe residual in my system? The Aspergillus I am wondering if I picked it up last year in Qld, and I don't know about the Klebsiella.

The severe SOB I am experiencing (not all the time, but intermitently) started on my trip to Qld last year after I camped alongside a sugarcane factory burning off great funnels of black and white smoke...and it then continued on my travels and I seemed to be reacting to everything - smoke, dust, damp etc...which makes sense with a Mast Cell Activation.

I am trying to piece it together. The specialist seemed alarmed that there had been such a drop in lung function.

I have tried to sumarise my Spirometry results over the years (attached) and would be very grateful for any light you or anyone could throw on them for me.

Thank you so much!