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@northoftheborder

Why did they only offer me palliative care then? None of the doctors suggested targeting the tumor with radiation therapy.

I completed eight cycles of chemotherapy with docitaxel and ADT, and six months later they added apalutamide, which dropped my PSA to 0.

Now I'm very afraid that the cancer will become resistant.

I asked my doctor about radiation therapy, and he said radium and lutetium would be used later. But I still don't understand why radiation therapy can't be used now?

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Replies to "@northoftheborder Why did they only offer me palliative care then? None of the doctors suggested targeting..."

@denis76 I can't answer for your oncology team. It could be because the evidence isn't as strong for benefits of going after the "mothership" with polymetastatic PCa as it is with oligometastatic, it could be that they're not convinced that this (new) approach is best for you, or they might just not be ready to adopt it yet.

On the bright side, the TITAN study showed that starting Apalutamide early with ADT can significantly delay castrate-resistance (when the study ended after 4½ years, nearly half of the participants *still* hadn't developed castrate resistance, and many of those had had PCa for years before the study started). So you're getting latest/best standard of care on that side.

I hope things go well.