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A note from Richard Wassersug PhD About the use of estradiol over ADT
Prostate Cancer | Last Active: Feb 22 10:55am | Replies (26)Comment receiving replies
Unbelievable info, Jeff! Thanks so much for reaching out to him and giving us that timely knowledge.
I have read some studies which suggest that it’s not the ADT which causes hormone resistance, but the cancer itself, which was of that type from the get go…
But now it seems that it’s the total number of cells that ultimately makes the difference and you need to be on ADT early in order to avoid cancer cell proliferation and conversion to hormone resistance…a real eye opener for all if us who’ve said ‘not yet, not yet’…
You must be very pleased since you have been on ADT for years and have probably wondered when it would stop working?But it looks like that will not happen anytime soon!🥳
Thanks again,
Phil
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@heavyphil
As you know I became castrate resistant 2 1/2 years after starting ADT. I’ve stayed on it since then, because not all the cells are resistant to it. My oncologist is pretty emphatic about my Not stopping it since I have BRCA2.
After eight years, I wonder if the side effects of it are really worth the risk of continuing it. Nubeqa worked perfectly to keep my PSA down even during the eight months I stopped taking Orgovyx, Figuring, as long as I’ve been on it my testosterone would never come back. Fat chance.
The one big benefit is that I don’t really have many annoying side effects from ADT.