@misst1970 Thank you, I found your message to be very informative and helpful. I developed osteoporosis at a young age. I have lupus as well. I took four years of a fosse act from 2013 to 2017 and then was put on a drug holiday and was being watched until the last couple years when I started losing more bone and this past December’s DEXA was the worst worst so I will be starting Tymlos on Tuesday. It’s scary and it was a hard decision dealing with the change it will bring to my life mentally and physically, but I think the best choice in my case so I can rebuild back some of my bone. I am 64 and my spine was a -3.5. My 2 choices after the two years on Tymlos are Fosamax or reclast but I have a little time to think about that though I am leaning towards reclast since it has a slightly better edge than Fosamax. I have an appointment at my doctors office on Tuesday. They will help me with my first injection. Fingers crossed that I don’t have any reactions.