@cdammen family history of cardiovascular issues- brother had a heart attack at age 54, mother has had a coronary bypass and has vascular dementia. I found that I have osteopenia in the lumbar spine (hips and femoral heads are better than average for my age, though). Estrogen is protective for cardiovascular system and bone density, so I’d like to take advantage of that. I’ve had a partial hysterectomy so I don’t need to worry about endometrial cancer, and I’m pretty active so DVT shouldn’t be an issue.