← Return to first PSA result post salvage RT — 0.086

Discussion
melvinw avatar

first PSA result post salvage RT — 0.086

Prostate Cancer | Last Active: Feb 15 6:22pm | Replies (9)

Comment receiving replies
Profile picture for melvinw @melvinw

@brianjarvis Yes to all that. I’ve also read that because PSMA PET scans are so new that docs are still trying to get a handle on what the data are actually telling us.

The hard facts I have in hand are: (1) it was nine years after my RARP when a palpable nodule was detected; (2) it was ten years after my RARP when my PSA rose above detection for the first time (0.11); the nodule showed significant uptake on the PSMA PET scan; (3) three months after my PSA rose to 0.11, and just before starting RT, my PSA remained unchanged (0.11, Quest; 0.094 Labcorp ultra sensitive); and (4) three months after finishing RT my PSA is 0.086.

Summing all that up, I caught and treated my recurrence about as early as possible. In reality, if the SUV max was 3 or 8 or 10, I don’t think that would have changed the course of things one bit. I’ve said this before, but it was regular DREs that first signaled a local recurrence. A PSA of 0.11 (or 0.094) without a palpable nodule probably would have put me on surveillance rather than a course of treatment. There but for the poke of a finger…

Jump to this post


Replies to "@brianjarvis Yes to all that. I’ve also read that because PSMA PET scans are so new..."

@melvinw Yes, PSMA PET scans are relatively new. There are currently three of them:
> trade name: Illuccix®: FDA Approved in December 2020

> trade name: PYLARIFY®: FDA approved in May 2021

> trade name: Posluma®: FDA approved in June 2023.

The difference between an SUVmax of 3, or 8, or 10, is that if the standard of care treatments didn’t work, the higher the SUVmax, the more effective the Pluvicto (Lutetium-177) treatments would be.

Good luck!