@jimmy05: My endocrinologist said once you start, you shouldn't go off because you can suffer more bone loss than when you first began in a short amount of time. You are taking reclast for bone growth and then Prolia "locks it in" (endocrinologist talk) as the Prolia slows bone break down. I have been on it for almost 6 years and never had a side effect until I went for my bi-annual injection and was told that on that particular day I wouldn't be receiving the Prolia version of denosumab but the new-on-the-market biosimilar, Jubbonti. I had terrible bladder pain that kept me in bed with a heating pad most of the day. I also made a video visit with my primary care doctor and got an antibiotic. I informed my endocrinologist that I would never have another Jubbonti injection. She got permission from my healthcare organization to allow me to continue with Prolia. But as an advisory, always drink plenty of water after your injections if you go that route. Glad to hear you are doing better.