Oxybutynin superior to placebo in reducing ADT-associated hot flashes

For me Megestrol works great. Within two days of starting, hot flashes were gone. i am currently taking half a dose and no sign of a hot flash.

@jeffmarc Thanks, Jeff! I've been taking Mirabegron (Myrbetriq) 50 mg unsuccessfully for urinary frequency, as well as having hot flashes. My urologist is considering 5mg Oxybutynin BID for both urinary frequency and hot flashes, but mentioned potential side effects of dry mouth, constipation, and cognitive loss. He commented that if Myrbetriq had been working well, he would have added venlafaxine for controlling hot flashes. I'm typically up at night 4-5 times, with 2 or more of those accompanied by hot flashes as well as throughout the day.

@jime51
A couple of people came into ancan.org and said that they were on oxybutynin For hot flashes and it worked really well. They didn’t mention any side effects.

Below are a number of drugs you can take for hot flashes, You could speak to your doctor about it. Venlafaxine is there of course. Not sure why the doctor didn’t consider just doing it.

Since Myrbetriq Didn’t work you might ask your doctor about Gemtesa. It may help with the incontinence problem. It’s the other recommended drug I know of for it.

@jeffmarc The urologist would have prescribed Venlafaxine if Myrbetriq were controlling nighttime urinary frequency. Since it hasn't, he's considering oxybutynin for both issues. Thanks for the additional resources!

My oncologist said that acupuncture worked for perhaps 80% of his patients. I had three sessions, and the therapy greatly reduced the number and intensity of the hot flashes. After a few months the effect was wearing off, so I went for a couple more sessions, and it was effective. Throughout my time on ADT, however, I did find that staying warm was a challenge. Even on a warm summer evening, I would need a sweatshirt.

@nikolai57 How does acupuncture treatment prostate cancer?

@tdoriausername
If you are on ADT, they can stop the hot flashes. I’ve heard quite a variety of results from it, I think 80% may be a little high.

ADT caused hot flashes are really the only thing Acupuncture will help with if you have prostate cancer.

@jeffmarc Jeff is correct. I was referring to hot flashes only. Sorry for the vague wording of my original post.