I have MAC disease on Arikayce 6 months and doing better inder direction of an Infectious Disease Dr.]. Pulmonologist also following since diagnosis of lung fibrosis/bronchiectasis put me on Brinsupri. After one month I had roseasea on cheeks, excema in area near mouth, and a blister on arm dermatologist thought might be skin cancer. I took myself off the med completely and the last problem has gone away but the two on the face are still present after two month off. I would not advise anyone to take it. The FDA approval was based on a very small pool of people.