@panarosmith It’s so encouraging to hear of folks that tolerated an aromatase inhibitor well. I hope it continues on for you! I was not so fortunate. I am 78 with history of neuropathy in my legs and joint issues in shoulder (new shoulder joint in 2021 and spine (lumbar fusion in 2023). My tumor was tiny without evidence of aggressive growth. Had a lumpectomy and radiation then figured why not take an AI? Side effects started slowly then became severe at 4-5 months in. Pain made sleep impossible and sleep deprivation made me moody and depressed. I tried another AI and got worse. Finally quit at the 7 months mark and have spent the time since then mopping up after the continuing side effects edema, urethral prolapse, venous insufficiency. On to good side, I have lost about 15 pounds, my hair has stopped falling out and my nails have come back. My risk of cancer went from 2.5% at 5 years to a bit below 5%. But I have a joy-filled life again! Best wishes to all with this disease and thank you for sharing your stories!!