Cymbalta severely fvcked me up, and I had only beenon it a short while at 20 mg. Just changing from bedtime to morning dose caused an extremely hypomanic response where I was driven to do a massive amount of cleaning and organizing, despite my chronic pain that was made worse day by day with the activity. The first night skipping it at bedtime, I had auditory hallucinations, what they call "brain zaps," and some dyskinesia. My week of activity before I was in literally too much pain to move, and I was in bed for 6 weeks, begging doctors for help, being told I'm crying in my sleep. Then I remembered I had some Baclofen a friend sent me years ago, and I inadvertently took too much and wound up losing awareness of a full day and eventually being taken to the hospital, where I was misdiagnosed with "psychosis," and they literally treated me like garbage. I had been put on Cymbalta a few years prior for a short while, and it caused me to faint and sustain a concussion, so I was reluctant to try it again, but mistakenly trusted the prescribing pharmacist at the clinic. Since that medication, any time I try anything for depression, I get worse side effects, twitching... the hospital had given me some sort of IV antipsychotic, which made things a LOT worse. I had sleep hallucinations for about a month - thankfully, not every night, but it was terrifying, and I feared I was losing my mind.