@climateguy

If and when I experience BCR, the trade-off between the side-effect burden of ADT and its potential curative benefit will be a major concern for me. In one of his videos, Dr. Kishan—whom I consulted a few weeks ago about his clinical trials—states that ADT improves BCR-free survival from 82% to 85%. In the same video, he also says that for every 8 people treated, 1 benefits.

I understand this to mean that if I undergo ADT, I have only about a 12.5% chance of a very modest improvement in outcomes (an increase from 82% to 85%), but a near-100% chance of experiencing side effects that many people find debilitating. I did briefly raise this concern with both Dr. Kishan and his physiian assistant, but we did not discuss it in detail since I had so many other questions for them, including whether I will be good candidate for MRI-guided SBRT given my pre-existing urinary issues: that is if and when I experience BCR.