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Anyone had success with Low-Dose Naltrexone for PEM, Chronic Fatigue?
Post-COVID Recovery & COVID-19 | Last Active: Feb 22 4:52pm | Replies (28)Comment receiving replies
@erinhastedt
Yes, LDN is one of those drugs that when it works it can be amazing.
It basically, does a reboot nightly of the immune system which helps reset all the normal parameters which have been messed with my virus action, age or even vaccine impact:
Low-Dose Naltrexone (LDN) improves Post-Exertional Malaise (PEM) and Chronic Fatigue symptoms through three primary pathways that "recalibrate" the body's response to stress and activity, the last link below tells how the below occurs:
1. LDN acts as a glial modulator to inhibit the release of inflammation markers.
2. Helps restore cellular energy
3. Boosts natural endorphins
Research articles:
https://pmc.ncbi.nlm.nih.gov/articles/PMC6954765/.
https://www.painspa.co.uk/low-dose-naltrexone-could-treat-long-covid-symptoms/.
Great paper on how LDN works in the body to help with Long Covid and auto-immune diseases:
https://meassociation.org.uk/wp-content/uploads/MEA-Summary-Review-Low-Dose-Naltrexone-LDN-in-MECFS-14.11.19.pdf
Replies to "@erinhastedt Yes, LDN is one of those drugs that when it works it can be amazing...."
@kathleen1314 - Thank you for the the links to articles. I do a lot of research and will check these out.
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@kathleen1314
My biggest question about LDN is, how long do you need to continue taking it? Does it eventually "reset" your system and allow you to discontinue use? Or are you on it forever? I haven't been able to get the answer from my DR. so am always curious what others think.