I was diagnosed with PC last fall with a gleason score of 8 with a significant tumor, and it had spread locally to adjacent lymph nodes. I decided against a full prostatectomy, since it had already spread outside my prostate, and had a TURP instead to help with urination then followed by ADT and radiation. I have been on lupron and Zytiga for a little more than three months, and I start radiation tomorrow. My PSA is now undetectable, and testosterone is similar. So the treatment is working well. However, I can't imagine taking these drugs for two years or more. I recently saw articles discussing estradiol patches for treating PC. The few studies have shown the patches to be just as effective with fewer nasty effects and a greater life quality than ADT.

However, when discussing this my urologist and oncologist there was minimal knowledge of the treatment method, neither were willing to prescribe estradiol patches, both showed minimal interest, nor direct me to clinical trials or other sources of information. I am not sure where to go from here, and I could really use some help.

Nice to find this support group and thanks.