Hi @christysjohnson - welcome to Mayo Clinic Connect. You and your husband have been through a lot of challenges with the two different types of coughing, fatigue, shortness of breath and night sweats.

I just have the coughing issue sometimes from my asthma, and it also affects me more at night or when I'm in meetings where I talk quite a bit. The continuous cough where you can't stop till you take one of those benzonates is also familiar to me. The sudden tightening in your husband's throat that seems to briefly cut off his airway and triggers coughing seems concerning, as of course his ability to breathe is paramount. I've not been perfect and have had to do another course of prednisone lately, but in general, taking a biologic, mepolizumab (Nucala) has really helped tamp my coughing down.

You and your husband have done an admirable job of getting him to different doctors who might assess and help him. The upcoming testing and balloon sinuplasty sound wise.

Feeling pretty overwhelmed and discouraged, and desperate for answers or direction at this point is hard. Hoping members here such as @drsharon @orangetiger @hopeful33250 @clachow @debbells18 will have some insights for you from their own experiences and some thoughts on how to get some relief and help for you and your husband. I'd also like you to meet @sueinmn.

How is your husband's sleep with experiencing these symptoms? How about your sleep?