← Return to Support for wives with the Orgovyx tornado: Needing an olive branch

Discussion
Comment receiving replies
Profile picture for jimgaudette @jimgaudette

@jeffmarc We are all unique and react differently. per PubMed:
Factors influencing T recovery after ADT:
1. DURATION
Longer exposure suppresses the hypothalamic-pituitary-testicular acis more deeply. Median time to T recovery rises dramatically with treatment length and is not linear. Multiple studies conclude that ADT duration is the single most important variable affecting recovery.
2. AGE
3. BASELINE T
4. MEDICAL
COMORBIDITIES

When I was 69, I was on ADT for six months with very mild side effects. After three months off, my T was 400. Four and a half years ago I started ADT again with only mild side effects, but they became much worse after two years. The third year was horrible. I have been off ADT for 16 months and my last T (two months ago) was 100. My blood pressure, blood sugar and red blood count returned to normal right away, but the hot flashes, emotional lability, depression, tiredness, muscle and bone loss have remained. I am treating these with exercise and am somewhat successful, but the hot flashes and emotional lability remain.

Jump to this post


Replies to "@jeffmarc We are all unique and react differently. per PubMed: Factors influencing T recovery after ADT:..."

@jimgaudette

I agree with your comments. There is a lot of recent work that now shows that ADT may not be very helpful for many men especially if you are older or have severe side effects. Watch this video: https://www.youtube.com/watch and https://www.youtube.com/watch

@jimgaudette
My experience seems to run counter to this standard.

Seven years on ADT
77 when I stopped it
My baseline testosterone was over 600
I’ve got plenty of comorbidities

I guess they’re just isn’t any real standard for how long it’s going to take

My blood sugar has never been a problem
My RBC and platelets have always been Below the minimum while on ADT
After six years of major hot flashes they have finally become warm flashes
I’ve got tumors in other areas but non-cancerous so far
Been on blood thinner for years
I haven’t found any year past the second or third that it’s gotten any worse. The last three or four is just about the same except the hot flashes are milder