@pesquallie It could have been that leuprolide ADTs (like Lupron, Eligard, Prostap, Camcevi, or Lucrin) would have those terrible side-effects for you, but other non-leuprolide ADTs (like Zoladex, Trelstar, Pamorelin, Decapeptyl, Firmagon, or Orgovyx), might have worked well for you.

Yes, it’s that way with many pharmaceuticals - sometimes it’s the active ingredient that causes problems; other times it’s the fillers. There’s no way to know except for trying others.

There is currently an AI tool to help determine if using ADT will be helpful (or not). As time goes on. Medicine continues to advance and provide more options.