I have had PMR for 13 months and have tapered to 5 mg. prednisone. I find I am in considerable pain until about 10 AM, then things improve and I have little pain the rest of the day. I take the 5 mg in the morning along with 1000 mg of Tylenol. The 8-hour time release Tylenol for arthritis is useless. 1000 mg. of Tylenol in the morning and also in the night when I get up to use the biffy really help. Recently my hands and wrists have been hurting. The past two days I could not lift a coffee cup with my right hand until about 10 AM. Such a strange disease. I have been trying to slowly taper but I think I am throwing in the towel and going to follow my rheumatologist's suggestion and try to get onto Kevzara. My blood levels are also low. And I am a walker and can walk well in the afternoon.