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Anybody out there have medication induced Osteoporosis?
Osteoporosis & Bone Health | Last Active: Feb 14 10:47am | Replies (43)Comment receiving replies
I took Effexor for over 20 years. Only after that did I learn it could cause osteoporosis. Even my internist was surprised, but he also thought you could get off of Effexor in two weeks. (It took two YEARS to get off of it!). I am off now and hoping I will re-gain some bone density. I don’t and won’t take osteoporosis drugs. There is some indication that I may regain SOME. I did start resistance training. We will see.
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@llynch17056 Oh. A cautionary tale in more ways than one. I wish you the best and I, too, am leery of the meds. Having been on different cocktails for decades I have learned to be so. All my best and if you have success please let us know.
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@llynch17056
I am so sorry, but glad that you are doing so well.
For those who are unaware with what you are dealing: "Effexor (venlafaxine), a serotonin-norepinephrine reuptake inhibitor (SNRI), is linked to accelerated bone loss and increased osteoporosis risk primarily by increasing osteoclast activity (bone-breaking cells) and decreasing osteoblast activity (bone-forming cells). By inhibiting serotonin reuptake, the medication may disrupt bone remodeling, leading to lower bone mineral density (BMD)"
It does this by increasing CTX (a marker for bone resorption/loss) and decreasing P1NP (a marker for bone formation), accelerating the rate at which bone is broken down.