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gaboslastresort avatar

Leg Weakness and Mobility Issues

Autoimmune Diseases | Last Active: Apr 7 7:50pm | Replies (134)

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Profile picture for sickofpasswordsu2 @sickofpasswordsu2

My first question is: Are you on any medication? I am asking because when I have a reaction to a drug, my muscles are hit big time. My neck, arms, legs become weak and have very limited movement - and the spasms as well as trying to turn my head is very painful. The CK sometimes is normal, but the SED and the CR are sometimes elevated. I am trying to get some pharmaceutical genetic testing done to see if my reactions (for the muscles) are a result of an impaired drug transport system. Like you, my ANA is high - over 1250 but everything else in the autoimmune area is fine.
BTW, even OTC drugs can affect the same way.

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Replies to "My first question is: Are you on any medication? I am asking because when I have..."

@sickofpasswordsu2

I also have similar experience with muscle weakness and joint stiffness during recent episode of bad cold - started in January. I had rhinitis that progressed into very bad long-lasting bronchitis. The test was negative for both COVID and Influenza A/B. My condition did not respond to Amoxicillin, but it did respond to Ceftin 250mg x 2 daily. Joint stiffness and muscle tightness in the legs started on Ceftin. Could it be a reaction to Ceftin?
My husband had the same cold and recovered in 5 days without any antibiotics. This makes me think that initial cold was due to some other virus, which in my case later progressed into bacterial infection. I still have joint stiffness and muscle tightness in the legs/calves that makes it difficult to walk.
For a reference, I have high ANA Titer with scleroderma (autoimmune condition), when my husband does not have autoimmune conditions. He recovered fast and without any complications.
Did anyone else have similar symptoms of weakness in the legs, muscle tightness in the calves, and joint stiffness during recent cold, and when on antibiotics?

@gaboslastresort and @sickofpasswordsu2 As for wondering about your medications causing leg weakness. I found out that they can cause problems with your muscles. You might see if you can make an appointment with your pharmacist and have a discussion about the side effects and interactions of the drugs that you are on. Drugs do wonderful things for us but they also cause problems!