Some people have some major side effects from Pluvicto, most don’t. I have heard at least 5 people talk about their experience, In some cases they had to have more time between doses because of the side effects.

I saw a webinar where they discussed a person who lit up the Pet scan With metastasis from head to Legs. He had one Pluvicto Treatment and it almost cleared his pet scan, But his side effects were so bad that he could not take any more treatments

Be aware that it works really well for 33% of people OK for 33% of people and not at all for 33% of people.
If you have certain genetic issues, either hereditary or somatic, it can affect how well Pluvicto Works. You can ask for a somatic test before doing Pluvicto To find out if you’ve got Genetic changes Due to the cancer.

If you have BRCA2 or ATM It seems to work better. If you have RB1, PTEN or TP53 They are Pluvicto resistant.
https://connect.mayoclinic.org/comment/1380711/
The guy who runs the reluctant brotherhood advanced prostate cancer forum had Pluvicto a few months ago. He’s had prostate cancer for 12 years and almost every treatment, including chemo. After two Pluvicto treatments, his PSA went to .05. He’s holding off any more treatments until his PSA starts to rise.

You just never know how successful it will be.