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← Return to Kevzara (sarilumab) to treat PMR
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Kevzara (sarilumab) to treat PMR
Polymyalgia Rheumatica (PMR) | Last Active: Jun 22 10:17am | Replies (206)Comment receiving replies
Good Morning, Kevzara, really only 28% success rate, that seems so scary. How did you find that rate out. Thanks, Ellen D.
Replies to "@lori62yb Good Morning, Kevzara, really only 28% success rate, that seems so scary. How did you..."
That 28% success rate depends on how you define success. The people enrolled in the study trial were said to have at least one PMR relapse during a Prednisone taper. The patients enrolled in the study were the ones who failed to achieve remission with the standard treatment with Prednisone. One could say that "Prednisone failed" these patients. Improvements were highest in patients with the most severe disease.
People are inclined to say that taking Prednisone is about "quality of life." My quality of life improved immensely when a biologic allowed me to taper off Prednisone.
https://pubmed.ncbi.nlm.nih.gov/40544861/
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The following link summarizes the actual SAPHYR study.
https://pubmed.ncbi.nlm.nih.gov/37792612/study.
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Patients who didn't have "success" with Kevzara needed substantially less Prednisone to control PMR. That in and of itself is deemed to be a success by medical professionals.
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@elleninz I did a search on Kevzara and their rate off success, in PMR remission.