@songfamily2025 It's a good question but I have no clear answer. I'm guessing you are right as regards ten years. With each passing year, my oncologist explained, my life expectancy looks better. The two year and then the five year mark both bode well. I don't mind being on letrozole at all. My bone density is still normal. The truth is, I'm very grateful this drug is keeping me going. I'm almost 72, and other co-morbities have made me face mortality in a way that isn't bad at all. I'm really enjoying life, a day at a time. Wishing you all the best, too, in every arena.