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Gloria Squitiro avatar

BHRT vs PHRT

Osteoporosis & Bone Health | Last Active: Feb 21 10:43am | Replies (47)

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@squitirogloria
Ok, after looking at the website to which you referenced, I think this is to what you are referring:
Physiologic Hormone Restoration Therapy® (PHRT) is a specialized, personalized approach to hormone therapy designed to mimic the body's natural, cyclical hormone production rather than providing a static, daily dose. It utilizes bioidentical hormones to match the body’s fluctuating, monthly rhythms.

Description and differences between PHRT, BHRT, HRT:
PHRT (Physiologic Hormone Restoration Therapy): Uses plant-based, bioidentical hormones tailored to match the body's natural, monthly cyclical needs, adjusting dosages throughout the month.
BHRT (Bioidentical Hormone Replacement Therapy): Uses plant-derived hormones that are chemically identical to human hormones, often customized via compounding for specific patient needs.
HRT (Conventional Hormone Replacement Therapy): Typically uses synthetic hormones or those derived from animal sources (like pregnant mares' urine) to treat hormone deficiency, often at fixed doses.

Key Differences:
Molecular Structure: BHRT and PHRT use hormones identical to human hormones, while traditional HRT uses synthetic or animal-derived versions.
Dosing Method: HRT uses standardized, fixed doses, while BHRT is often customized to individual levels. PHRT takes this further by varying the dose throughout the month to mimic natural cycles.
Source: BHRT/PHRT are generally derived from plant sources (soy/yams).

BHRT has been used by doctors freqently, in a varying dose, to mimic natural cycles. So I view this as BHRT varied to mimic natural cycles. If it works for anyone then that is great.

I have used BHRT for over 30 years and did not find that the varying dose worked well for me. The problem that I found is that you cannot mimic a natural body cycle because the natural younger body holds hormones and keeps some level of hormone in the body at all times. That does not happen as well in menopause and may fluctuate erratically . So it was more likely that I would have a problem with vaginal or bladder issues when I tried the "mimic natural cycles" method because my hormones were so erratic; that is why we have hot flashes, those wild fluctuations up and down.

So a steady amount of homone works well for me without the risks of wild fluctuations that could cause bleeding, breast cysts, hot flashes etc.

It might work in a perimenopause situation, but I doubt that also since the body has little to no progresterone in that time period and needs a constant supplementation to avoid anxiety attacks and anger surges.

If you try this please let us know how it works for you. That is what is most important, how it works for you.

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Replies to "@squitirogloria Ok, after looking at the website to which you referenced, I think this is to..."

@kathleen1314 You're always so helpful and kind, Kathleen; I super appreciate you.

I should be having an intake evaluation re hormonal therapy within the next week. Like many people, I was under the impression that it caused cancer, when it seems it can actually prevent it. What a disservice to women.

I don't think I'll ever see my fracture as a blessing, but there are silver linings.

a. I'm meeting people like you
b. I'm more determined than ever to do what it takes to go into the next third of my life being optimally fit so that I can enjoy everything life has to offer
c. I'm determined to work hard to be osteoporosis-free without pharmaceuticals
d. I might have discovered hormonal therapy, which seems like it can do wonders on so many levels. Who knew?!