@jemollica --Thanks for sharing about your son,
I'm being reminded that each of us has unique needs via our brain, body-- and consciousness. (Consequently, your son's condition improved with a lowering of Xcopri, mine improved with an increasing) Of course all of this can change again..but it IS so important that we have skilled medical help--and for my son-- it's also important that he factors in non-chemical influences (he's starting to exercise, starting to meditate, etc.