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Profile picture for Miriam, Volunteer Mentor @mir123

@brooklyn22 Just to add in. If the question is do Aromatase Inhibitors such as letrozole and others keep estrogen positive breast cancer from coming back and/or spreading--the answer is yes. Tamoxifen does the same. The odds are different for each person. Or are you asking something different? I've been on letrozole for 3 1/2 years. No side effects. My rare aggressive cancer has not reappeared--a good sign the letrozole is working. (I did not have chemo due to kidney disease). Hope this clarifies.

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Replies to "@brooklyn22 Just to add in. If the question is do Aromatase Inhibitors such as letrozole and..."

@mir123 Hi, I am so glad to hear that you have no side effect with Letrozole. May I ask how many years you need to take? As you mentioned that you had rare aggressive one So I guess you may need to take up to 10 years? My one was not aggressive that I need to take 5 years. I am on only 6 months with mild side effect and hoping no major one for much longer years. I mean at least for 3 years.

@mir123 hi asking percentage rate of taking Aromatase Inhibitors vs Not- I’m going by the science genomic test results my Onco Score (3) Ki67-10 very slow growing I finished radiation Oct ‘25 had post Mamography last month then will do again in July - turned 71 in Dec BRCA Neg- I honestly thought once I had lumpectomy radiation I’m done with the nightmare - I’m still researching natural for E&P positive HER2 - I hear grape seed very good proven - I wish us all good luck in whichever path we are on.