Blood pressure meds making neuropathy worse?

Posted by 32cooper32 @32cooper32, 3 days ago

I started having peripheral neuropathy symptoms 4 years ago. Very minor at first and then it has progressed to the point of continuous pain in the feet even with maximum gabapentin. I do not have diabetes and there is no specified cause of the neuropathy.

I started seeing a GP at 65 who started treating me for high blood pressure. Increased blood pressure meds 3 times over 6 months and it was during that time the neuropathy started (or at lease I became aware of it enough to start asking questions about numbness in the small toe on one foot). Since then it has been 4 additional times of going off blood pressure meds (PB stabilizes) and the neuropathy stabilizes and then when BP goes up starting meds and the neuropathy gets worse. The problem with increased neuropathy occurs within 3-5 days of restarting BP meds.

Anyone else seem to have this issue?

Interested in more discussions like this? Go to the Neuropathy Support Group.

Profile picture for John, Volunteer Mentor @johnbishop

@ray666 - Hi Ray! Happy Tuesday to you also my friend! My fall recovery is going well. My eye still has a bruise under and around the edge but it's getting lighter. The scar is actually hard to see in the old man face wrinkles and looks to be healing really well. I just keep a little Vaseline on it daily like the PA at the ER that stitched me up recommended. I'm always concerned about new meds and looking up any possible side effects fearing the worse. Sometimes it makes it difficult to weigh the benefits with the risks. The longer I live I seem to feel like having a glass that is half full feels much better than having one that is half empty. 🙃

Hoping your day is a good one! I think I'm going to venture outside and shovel the snow off our deck (not a big job) and get a little exercise in and test my heated vest to make sure it's still working 🙂

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Hi, John. Snow off the deck? Heated vest? My gosh, you might consider moving to Colorado. We're having spring-like weather. That's surprising – also, a little alarming. When I first moved out here, our winters were legendary: snow piled windowsill high. These past few years? I feel silly even tossing a snow shovel in the back of my Jeep. I feel the same about adding meds. If I remember correctly, my PCP had me taking Amlodipine some years ago, and for a reason that's lost on me now, she took me off of it. I've just left her a message, asking about Amlodipine and any side effects possibly related to PN symptoms. Ah, the ol' glass half full. etc., question! For me, definitely not the empty glass. But between the full glass and the empty glass? Mmm? That's a puzzler. It depends. In most cases, I'd choose the full glass – unless I'm reading. If I'm reading, I'd rather spill a half glass on the $35 book I'm holding. Less mess. 🙂 –Ray (@ray666)

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Profile picture for 32cooper32 @32cooper32

@ray666
Ray,
Yes some of the drugs that has caused my problems include Amlodipine and most recently Nebivolol. The increase in pain and numbness in the feet coincide to me restarting BP Meds every time. Fun choice high blood pressure or increased neuropathy.

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That's a heck of a fun choice, isn't it, @32cooper32? It's like being asked, Which would you prefer? Hanging? Or a firing squad? 🙂 –Ray (@ray666)

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Profile picture for Ray Kemble @ray666

Hi, John (@johnbishop)

First, how are you feeling? How's your recovery going?

Thank you for these links! I'll check them out later this morning. I know that my PN can progress, and that progression is often just the nature of the disease. I'm prepared to accept that. At the same time, however, I find the coincidence – the adding of Amlodipine to my daily meds, and a slight if detectable worsening of my balance – at least worth asking about.

I wish you a fine Tuesday, John!
Ray (@ray666)

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@ray666
Hi Ray….Im on a few BP meds…I’ve done alittle looking previously to see if they could be causing my PN. I wasn’t ever able to find anything credible. One I take is amlodipine…it is possible that your balance is a bit worse due to it. But probably not because it’s making your PN worse, rather a side effect is lightheadedness/ dizziness which would aggravate balance. Drs are very cautious about prescribing additional BP meds to older folks as their balance systems are fragile…even w/o PN. One thing to watch with Amlodipine is swelling in the feet/legs..which is quite common…hopefully just 5mg won’t cause this.
Best of luck.
Steve

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Profile picture for stallen @stallen

@ray666
Hi Ray….Im on a few BP meds…I’ve done alittle looking previously to see if they could be causing my PN. I wasn’t ever able to find anything credible. One I take is amlodipine…it is possible that your balance is a bit worse due to it. But probably not because it’s making your PN worse, rather a side effect is lightheadedness/ dizziness which would aggravate balance. Drs are very cautious about prescribing additional BP meds to older folks as their balance systems are fragile…even w/o PN. One thing to watch with Amlodipine is swelling in the feet/legs..which is quite common…hopefully just 5mg won’t cause this.
Best of luck.
Steve

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Hi, @stallen! I've been concerned about Amlodipine all along. I may have mentioned that my PCP had prescribed it for me several years ago, but then because of some side effects (which they were, I've forgotten), she took me off it. You mention swollen feet. Well, guess what? My feet are swollen. My PCP has invited me to come in so we might discuss an alternative to the Amlodipine. Thank you for your insights! Very best wishes, Ray (@ray666)

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Profile picture for Ray Kemble @ray666

Hi, @stallen! I've been concerned about Amlodipine all along. I may have mentioned that my PCP had prescribed it for me several years ago, but then because of some side effects (which they were, I've forgotten), she took me off it. You mention swollen feet. Well, guess what? My feet are swollen. My PCP has invited me to come in so we might discuss an alternative to the Amlodipine. Thank you for your insights! Very best wishes, Ray (@ray666)

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@ray666
Ray…I’ve just been reading today about aged garlic for high blood pressure ( not regular garlic). It appears to show some benefit. The NIH did a small study which showed it worked. Give it a google.
Steve

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Profile picture for phyllisq @phyllisq

I just stopped my cholesterol meds because I am frightened about how quickly I am losing function in my legs. I feel as if I am on my own trying to figure out what is going on with my body. My legs are so weak I have trouble standing up for more than minutes. I’ve been told there is no treatment for neuropathy. I am starting acupuncture today - my idea, not referred by doctor. The only help through this whole ordeal is talking to other people going through the same thing. I see that while there are commonalities each case is unique.

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@phyllisq have you had MRI's of your spine to make certain it's not spinal stenosis? Just a thought.. that could be serious.

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Profile picture for stallen @stallen

@ray666
Ray…I’ve just been reading today about aged garlic for high blood pressure ( not regular garlic). It appears to show some benefit. The NIH did a small study which showed it worked. Give it a google.
Steve

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Thank you, Steve! (@stallen) I will give it a Google. Luckily I'm one of those who loves garlic. 🙂 I've an apointment to talk to my PCP next Monday about Amlodipine, dizziness (balance), etc. I'm pretty she'll tak me off of it, especally after she sees my swollen left foot. My left foot is the most swollen because of a long and deep septic wound I suffered last year that had destroyed many of my lesser blood vessels, vessels that otherwise would carry fluids up and out of my lower extremities. –Ray

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My symptoms started right after starting blood pressure meds.

In my research Hydralazine is one of the four I take with a known side-effect of neuropathy.

My PCP won't let me change the meds and I just had my cervical MRI which shows mild foraminal narrowing at c5.

I am going to ask my Cardiologist to adjust my meds next month. I would love to avoid steroid injection or surgery.

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