This seems to be a good topic for me this week as the caregiver with a husband who has MCI. We took a trip 1 1/2 hour from where we live to see a grandson who flew in from Canada, play ice hockey. well, there was drama. Driving was a big issue. He struggled, and when I took the wheel, he was so anxious, that we had more drama. It was obvious he didn't want to be uprooted from home even though we had been planning the trip. It's all so overwhelming. We had to stop to do the grandson's laundry - that's another story - but he just stood in the front of the laundrymat, not sure what he was supposed to do or wanted to do. Th en something happened to his phone, a daily, up and down, as he hits things on the phone, and then something happens for me to figur eout. When I asked him or help, at the laundry mat he struggled. I found with MCI, he's almost child-like, not sure what to do, when or how to do things. Yet, he's still independent, unless something happens, and it triggers anxiety, somewhat angry and/or defensive, and just uncomfortable in "confusing" settings. I think the biggest challenge or hurdle for me - and I'm sure any caregiver - is just trying to figure everything out on our own. He's on lequembe but I'm not sure if after the 9th infusion, I'm noticing any change. Does anyone out there on leguembe, see any progress. Thanks.