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@red350
I had a very similar situation, only in reverse. A trace, stable pericardial effusion suddenly developed into a cardiac tamponade, for which I had a pericardiocentesis to drain the fluid. The procedure caused severe pericarditis, which became recurrent, despite double doses of colchicine, along with ibuprofen. After five months in and out of the hospital, a rheumatoid cardiologist suggested rilonacept. It made all the difference in the world for me. I have had no pain, no recurrences, and more energy than I have had in nearly nine months. If you rebound after tapering off your various meds, you may want to consider it. Rilonacept has given me my life back!

I will soon go on an international trip and need to figure out how to keep the rilonacept cool throughout the 3 weeks, while on planes and buses. So far I have been happy with my 4AllFamily Explorer cooler, but it means the vials cannot be in original packaging as required by customs in the countries I will be visiting. Does none have experience with this? Or with a larger cooler that could accommodate a 4 inch cube shaped box?

Thank you and good luck!

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Replies to "@red350 I had a very similar situation, only in reverse. A trace, stable pericardial effusion suddenly..."

@crraining, welcome to Mayo Clinic Connect. I am glad to see you comment and connect here with red350.

I want to address your travel concerns and introduce you to @jmpuyallup who has commented about medical grade coolers for medication.

I also found some information you may want to review if you haven’t seen it:
Traveling With Medication: https://travelmedicineadvisor.com/how-to-travel-on-a-plane-with-medicine-that-needs-refrigeration/

You mention feeling good with no pain and more energy attributed to Rilonacept. How long will you need to take it?