Connect
← Return to Are castration sensitive prostate cancer patients being over treated?
Discussion
Are castration sensitive prostate cancer patients being over treated?
Prostate Cancer | Last Active: Feb 7 10:53am | Replies (37)Comment receiving replies
On a different (but related) note, the last research I saw suggested that ADT holidays were safe for earlier-stage aggressive prostate cancer, but not for stage 4, where outcomes were still a little worse after "holidays".
I'm hoping additional research will refine that a bit, and that maybe they'll discover that holidays are safe for *some* stage-4 situations as well (I don't mean just one isolated study, but major, reproduceable findings).
I'd love an ADT holiday, but with my mCSPC perfectly controlled by ADT+Apalutamide for nearly 4½ years now (and me tolerating the side-effects surprisingly well), I'm nervous about prodding the sleeping bear. If my cancer is happy staying in full hibernation with the current regimen, I want a lot more medical evidence before I risk disturbing it.
Replies to "On a different (but related) note, the last research I saw suggested that ADT holidays were..."
@northoftheborder
This is true. The more aggressive the original prostate cancer case the less likely waiting for it to get worse makes sense. If you have an aggressive case, you probably need aggressive treatment.
That’s one reason castrate resistant cases were not included in this discussion.
Connect
Of course, if I weren't tolerating ADT+Apalutamide well — if I were showing a serious risk of kidney, liver, or heart disease, for example — that might be enough to tip the scales towards an ADT holiday: there's no point surving cancer just to die of liver failure. But very fortunately, I'm not experiencing any of that (at least, not yet) — just the normal, non-life-threatening side-effects.