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Transdermal HRT

Osteoporosis & Bone Health | Last Active: Feb 18 7:13pm | Replies (298)

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@kathleen1314
I am very interested and have felt hopeless…. I had two injections of Prolia (denosumab) approx six
Months apart and had many severe side effects. (See manufacturer Amgen’s lusting if severe side effects. I experienced so many and more which they have since listed. Drugs.com. UK medical and many medical institutions. Diagnosed by dentist which is good place to start w pain and agonies. Has affected small bones of ears with severe pain, numeroys hearing problems ans seen by otologist and two audiologists. No one should have injections withoyt careful study. Suggest not taking if react to many thinfs. Prolua had black box warning. Vit D and Blood calcium levels are significant in use and needs to be watched prior and during use if drug. Suggest see an endocrinologist rather than General or internal medicine. Reas and study carefully and discuss with dentist and ask questions. My life is destroyed. Pain worsens throughout my head without relief. Some major medical centers are researching. Mayo in Rochester is one. Can cause necrosis of hip/femoral heads more likely but jaw is also in danger. Rare but happens and if it is your but there is little help except long journey with antibiotics, steroids which may worsen possibility of infection, and may require bone replacement surgery, obvious need for pain relief, etc. not to take this lightly! I regret trusting and having ut. Some drs have said, “I have never seen anything like this but this is what it is.”

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Replies to "@kathleen1314 I am very interested and have felt hopeless…. I had two injections of Prolia (denosumab)..."

@jimiwho
This sounds most like a Prolia reaction. Prolia has listed side effects of necrosis of the jaw and osteonecrosis of the external auditory canal (bone death/breakdown in the ear canal.
This may be exaceberated by steriod use, but the Prolia really seems to be the problem.
I am so sorry that you are going thru this reaction. I was lucky I just couldn't take the osteoporosis drugs which we prescribed. My friend who was fracturing and stopped after she began strontium citrate says that we won the bone lottery.
You might try strontium citrate; it is an earth mineral found in most ground water and food; we just take it at therapeutic dose level of 680mg nightly.