@danpinkston24
Well, all I can tell you is speak to your doctor and check the research to share with your doctor. Plus, posing the question to copilot where it can evaluate all the research and align with your symptoms would be helpful to you I think.
Here is what I see in research:
Coenzyme Q10 (CoQ10) supplementation (typically 100–600 mg/day) is a promising, safe, and effective treatment to reduce statin-induced muscle symptoms (SAMS), including fatigue, weakness, pain, and cramps. Studies show CoQ10 can significantly improve these symptoms and reduce fatigue by 50% or more, often used to help patients continue their necessary cholesterol-lowering medication.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6054172/.
Following this lead-in phase, the confirmed myalgics were randomized to either placebo or 600 mg CoQ10/d. This dosage was chosen because the usually recommended dosage of ubiquinol or CoQ10 is 200 mg/d, and prior studies have used 100 or 200 mg/d. with this caveat:
Conclusions
Mechanistic studies and deductive reasoning suggest that CoQ10 dysregulation could be the cause, or could at least contribute, to SAMS. Clinical studies, however, have not documented its effectiveness in treating SAMS. Consequently, the present role of CoQ10 supplementation in managing SAMS is limited.
a systemic review:
https://pmc.ncbi.nlm.nih.gov/articles/PMC11441719/.
An American Heart Association paper:
In the present meta-analysis, 6 newly published RCT
studies were included, and the effect of CoQ10 supplementation on statin-induced myopathy in 12 RCTs with 575
patients was comprehensively evaluated. In contrast to the
previous meta-analysis, the present study demonstrated that
CoQ10 supplementation ameliorated SAMSs, such as muscle
pain, muscle weakness, muscle cramps, and muscle tiredness, independent of administration doses of CoQ10 (100–
600 mg/d) or CoQ10 supplementation time (30 days to
3 months).
https://www.ahajournals.org/doi/pdf/10.1161/JAHA.118.009835).&text=model).,;%20WMD%2C%20weighted%20mean%20difference.&text=change%20in%20muscle%20pain%20score,according%20to%20year%20of%20publication.&text=indicates%20confidence%20interval;%20ID%2C%20identification,;%20WMD%2C%20weighted%20mean%20difference.&text=model).,;%20WMD%2C%20weighted%20mean%20difference.&text=indicates%20confidence%20interval;%20ID%2C%20identification,;%20WMD%2C%20weighted%20mean%20difference.