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Profile picture for mcchesney @kathleen1314

Based on your description, you have likely experienced persistent statin-induced exercise intolerance or myopathy, even though you have stopped taking 80mg of atorvastatin. While symptoms usually resolve within 5 weeks of stopping, persistent, or long-term fatigue, often described as "flu-like" or "chronic fatigue," can occur due to potential damage to mitochondria and cellular metabolism during the 10-month, high-dose usage. It is reassuring that all your lab work (liver, kidneys, creatinine kinase) is normal.
I am not sure if you took coQ10 while on your statin?
Statin-induced mitochondrial dysfunction and muscle fatigue can persist for months after stopping the medication, but in most cases, it is reversible, though recovery time varies. While side effects often resolve within weeks, lingering exercise intolerance can last for several months. Recovery involves restoring ubiquinone (CoQ10) levels, which are depleted by statins.
CoQ10 Supplementation: Some individuals with statin-induced fatigue report improvement with Coenzyme Q10 (CoQ10) supplements, although you should discuss this with your doctor
Plus, an appointment with a neurologist or a cardiologist might be helpful.
https://pubmed.ncbi.nlm.nih.gov/12011782/
https://www.ahajournals.org/doi/10.1161/circulationaha.114.013189.
https://drmagaziner.com/heart-health/when-statins-cause-fatigue-and-muscle-pain/.

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Replies to "Based on your description, you have likely experienced persistent statin-induced exercise intolerance or myopathy, even though..."

@kathleen1314 Thank you so much! I am taking CoQ10, but wonder what dosage you would recommend?