@rocksology I too am 68 years old and was diagnosed with PMR in February 2025. I also have spinal stenosis which I thought was the main problem. Although prednisone and Actemra have been working extremely well for my PMR issues, the spinal stenosis/lumbar arthritis was causing crushing pain, probably exacerbated by the PMR. before I was able to see a rheumatologist, a general practitioner who wasn’t looking for PMR put me on Cymbalta for nerve pain. I started at 30 mg which wasn’t much of a help, but it was a low enough dose to help my brain get used to having the Cymbalta. After a few months, I went up to 60 mg which helped the nerve and muscular skeletal pain dramatically. during the past month and a half. I decided to start taping off of Cymbalta and I have to say that the nerve pain from the spinal stenosis is back but my PMR symptoms seem to be under control and make the spinal stenosis symptoms. Much more tolerable. Please talk with your doctor about starting on 30 mg of Cymbalta for a few weeks, which again, really didn’t help with the pain at all, but after a few weeks of being on 60 mg I found a huge relief. being that I am not a doctor myself I just went along with what the regular general practitioner was having me do last year. If you are on prednisone right now that should be helping if you are on a high enough dose, but I really feel that the prednisone with the Cymbalta truly kept me from going crazy. The pain was so excruciating. I too felt like I was at least 85 years old. My mother lived to be 94 and I would say to my family members that I feel older than my own mother, and this was at the age of 67. Good luck!