I used cryotherapy throughout my 8 rounds of chemo. I did the cold therapy only while receiving oxaliplatin. It was not easy to do this but I felt it was a short term discomfort to diminish a long term possibility of neuropathy. After chemo #4 I started to use light gloves and socks while wearing the mitts and socks. After chemo #6 I started to wear the cold packs for 15 minutes and take a 5 minute break. I had two sets of packs. Half way through I’d use the second set. My oncology naturopath and nutritionist had me start Vit B6 and lions mane as supplements after round #6. I wish I had known about this earlier. I stopped the Vit B6 when my chemo ended.
I had cold sensitivity in my hands between treatments starting after round #4. It progressively increased. I had some numbing and pain in my hands. I had 8 rounds of chemo. After two weeks of no chemo the cold sensitivity was better. I am 5 weeks out now and have no signs of neuropathy-no cold sensitivity. I believe the cryotherapy helped!!