← Return to Concerned about increase in CA 19 score during treatment

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@mcharlesfrancis agreed. My husbands CA19-9 was very elevated after he developed jaundice, they discovered his bike duct was blocked with CT and saw the tumor only with MRI (MRCP). It then dropped again after stints were placed with ERCp, biopsy was positive for PADC. Since his stints were placed his CA9-19 has been normal. And CT scans do not show tumor. I often wonder why they only do CT scans when the tumor isn’t visible.

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Replies to "@mcharlesfrancis agreed. My husbands CA19-9 was very elevated after he developed jaundice, they discovered his bike..."

@yellie You raise a good question about use of CT vs MRI regarding tumor detection and surveillance and it is a common point of confusion for the lay person.. I have spoken to several radiologists for their response.

CT is usually the first test because it’s fast, widely available (especially in the ER), and excellent for seeing things like bile duct blockage, liver spread, lymph nodes, and surgical anatomy. It’s also much less expensive and easier for very ill patients to tolerate. So when time is of the essence because the patient is experiencing acute pain and discomfort from symptoms, the CT is specified in diagnostic protocols.

MRI/MRCP is more sensitive for small pancreatic and bile duct tumors, but it takes longer, is more expensive, and isn’t always available urgently—so it’s often used after CT when more detail is needed.

Even when a tumor isn’t clearly visible on CT, CT is still very useful for monitoring spread, treatment response, and overall anatomy, which is why it remains the standard follow-up scan.

If a patient is stable and there’s no urgency, they absolutely can ask their team whether MRI/MRCP would add useful information.

@yellie Immediately get to a center that specializes in adenocarcinoma and have it removed. He is very lucky that it has been caught so soon. Dr. Evens at Froedtert in Wi is the best surgeon in US for pancreas cancer.