Anyone experience hand-foot syndrome from chemotherapy?

Posted by lindask60 @lindask60, Jan 25 12:29pm

My husband developed a rare reaction to chemo on his hands and feet. It was so bad they canceled his last infusion…bright red, swollen, extremely painful to touch, open sours, peals after a while. Has anyone else experienced this and what have you done for it. He has been referred to dermatologist at Duke and Kansas, but would just like to know if you may have tried something that will make him more comfortable. It has gotten better, but he has his next infusion on Thursday. Thank you so much ❤️

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

When a friend learned half a year ago that I had SBRT for my prostate cancer, and I was feeling low, he tried to encourage me. Then he told me (I didn't know before) that he had a more advanced PC than mine, he had a chemo treatment, but his care team canceled the next infusion, his body could not take it. In lieu, the way he described it to me, they did a brachytherapy. You may ask your husband's oncologist about brachy. My friend who is much older than me said it has been several years since his diagnosis, and he still here, so I should not worry too much about my less advanced PC. What stage is your husband's and what other treatment did he have?

REPLY

Hello, thank you for responding. Unfortunately, my husband has stage 4 aggressive. He is also in hormone treatment. It has metastasized to his ribs, spine, femur and pelvis, and lymph nodes in the chest and near spine. He has not tried anything else.
Ps. I just did some research and it can’t be done on my husband. I sure appreciate your suggestion, tho. 😊

REPLY

Could it be a reaction to the steroids they give right before the chemo?
Just a thought I had??
My husband has stage 4 and all over his body and got diagnosed a year ago and started Firmagon and Zytiga and prednisone and then chemo (docetaxel) over the summer, fell fine other than the numbness in the fingers and toes but it was minimal and only near the end though he used the chemo mittens and booties too- don't know if it helped or not.

REPLY

Thank you so much for your response. We hadn’t thought about it being due to the steroids. We assumed it was from the docetaxel. He did get the mitts, and they helped but only just a bit. He, like your husband, also has numbness in his fingers and toes.
I appreciate your thoughts, and pray your husband is doing well.

REPLY

Mife wife had chemo treatments, yrs ago, I would massage her hands & feet, as tht seemed to be where chemo would settle, others had problems, yet she had less! Just a FYI!

REPLY

@lindask60, hand-foot syndrome (HFS), also called palmar-plantar erythrodysesthesia, is a side effect of some types of chemotherapy. The most common chemo drugs that can cause this are:
5-fluorouracil (5-FU)
capecitabine (Xeloda)
docetaxel (Taxotere)
cytarabine (Cytosar)
doxorubicin (Adriamycin)
liposomal doxorubicin (Doxil)

Here's more info
- Chemotherapy side effect: hand-foot syndrome (palmar-plantar erythrodysesthesia) https://www.mdanderson.org/cancerwise/chemotherapy-side-effect--hand-foot-syndrome.h00-159459267.html

Did the dermatologist prescribed anything like a steroid cream? Was your husband able to continue with treatment? How is he doing?

REPLY

I sure hope the dermatologist can help him.

My husband will be starting chemo (dosetaxel) next week. As part of the protocol they use the cooling mitts and booties. I sure hope it helps (he is also stage 4 with much the same spread as your husband). He is already on relugolix and they are adding another one.

REPLY

I am so sorry to hear about your husband. My husband did purchase cooling gloves after the fact. His skin had already started being affected. He found them to be too cold, so only put in one of the cooling packs on the top of his hand, where the problem was. I truly hope that all goes well, and I appreciate, so much, your response.

REPLY
Profile picture for Colleen Young, Connect Director @colleenyoung

@lindask60, hand-foot syndrome (HFS), also called palmar-plantar erythrodysesthesia, is a side effect of some types of chemotherapy. The most common chemo drugs that can cause this are:
5-fluorouracil (5-FU)
capecitabine (Xeloda)
docetaxel (Taxotere)
cytarabine (Cytosar)
doxorubicin (Adriamycin)
liposomal doxorubicin (Doxil)

Here's more info
- Chemotherapy side effect: hand-foot syndrome (palmar-plantar erythrodysesthesia) https://www.mdanderson.org/cancerwise/chemotherapy-side-effect--hand-foot-syndrome.h00-159459267.html

Did the dermatologist prescribed anything like a steroid cream? Was your husband able to continue with treatment? How is he doing?

Jump to this post

@colleenyoung thank you so much for your response. They determined it was not hand foot syndrome, but a rare reaction called something I don’t remember.
Yes, the Dr did prescribe a steroid cream which helped some. He had to miss one infusion due to the severity. They didn’t want permanent nerve damage as he also has numbness in his fingers and toes. I sure appreciate your input…thank you for responding!

REPLY
Please sign in or register to post a reply.