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Weighing the cancer risk reduction & quality-of-life cost of ADT?
Prostate Cancer | Last Active: 5 hours ago | Replies (88)Comment receiving replies
@jeffmarc Hi Jeff
I was wondering how have you been on adt so long. Doesn’t that usually wear off in 3 years or so ? I have stage 4 prostate cancer psa was 600. Started adt and zytiga 14 months ago. Psa has been 0.1 for the last 9 months
Thank you in advance
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@dietzpagan
2.5 years after I started zytiga, I became castrate resistant, Which means the ADT drug didn’t really stop my PSA from rising. The thing is not all cancer cells are resistant so my oncologist has kept me on ADT for eight years. Because I have BRCA2, she wants to keep me covered. If I reduce my ARPI drugs by just a little, my PSA rises very fast.
They put me on Zytiga when I became castrate resistant, But it caused me a lot of problems, including four Afib events. At that point, 2.5 years after starting Zytiga, my oncologist put me on Nubeqa. She actually put me on a PARP Inhibitor but after five days, I said let’s switch to Nubeqa And she agreed. That has kept me undetectable for 26 months. Still going strong after 16 years.