Prostate cancer goes dormant, What really happens?
Here is an article I just received today that discusses the issue of prostate cancer going dormant, with quite a good amount of detail.
It also discusses some scary things that can bring it back.
https://www.nature.com/articles/d41586-025-04149-3
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So, interesting.
I read through this.
Intuitively it makes sense.
I pondered, looked back at my clinical history...
I finished triplet therapy in May 17, My PCa went "dormant" until it didn't.
Coincidentally, it's return coincided with the onset of Afib...I'm at 20 months of "dormancy" after completing doublet therapy., PSA is stable.
In October I experienced multiple TIAs over a three day stood, dry brief, no cause identified, all diagnostic imaging, labs and physical exams negative.
Will that "trigger" the dormant cell to become active? Labs in January were stable, no change. So, yes, no...we don't know nor will we be able to say with any definitive scientific basis if the July labs show activity...
But, if they do, that would be "two for two!"
Kevin
Study of one as they say, anecdotal...
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1 Reactionhello, the doctor commented it was found during the operation itself.
@rich9164809
I would sure like to find out how they did that. What did they see that showed you had dormant cells? That’s something you would see in a blood test, maybe. If it settles in an organ, how can you find it During surgery? Strange!!
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2 ReactionsWell...that was a thoroughly depressing way to start my Tuesday. The thing that caught my eye, was that the article said that these cells leave the tumor fairly early and go to wherever they are going to go: bone or lymph nodes. "Great." Something new to worry about for the next 15 years as I hope in general, that my pT3b type of prostate cancer won't come back "within" the first five years, as occurs 25-50% of the time. Thanks for the article though. I downloaded it. Hopefully I will not have to review it in 10-15 years.
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2 Reactions@rlpostrp Don’t read too much into all these articles - informative as they may be. These are research articles and as such, they delve into the nooks and crannies which have not been previously explored.
I have no doubt that there will be many more articles based on this one which either support, repudiate or add a new twist to it - and more worry!🤯
There’s a reason they say that you never want to know how the sausage is made…cause if you did, you’d never eat it! Similarly, these articles - and I read them too, believe me - can ruin your ability to celebrate and enjoy your successful treatment. I guess we’ve never recovered from the shock of our initial diagnosis and we’re trying to anticipate the next calamity.
I think we’ve all gotten so used to doomscrolling; remember when we’d actually have to get off our fat butts and go to a library to first even begin to learn about something?? Using the dreaded card catalog?? We probably wouldn’t, just say screw it and turn on the ballgame…now it’s just too freakin easy!!
Phil
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