← Return to Stopping Immunotherapy for Metastatic Melanoma due to Toxicity

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Profile picture for songinmyheart54 @songinmyheart54

I have been on keytruda since 2022 and will have to stay on it every 3 weeks forever. I was diagnosed with state 4 metastasized melanoma in my lung inoperable. I responded quickly to keytruda and went into remission very quickly but because melanoma hides and could come back anytime I have to stay on it.
This is my 4th cancer since 2014.
Breast, melanoma on shoulder, thyroid and now melanoma in lung.
It has damaged my heart but medication is taken care of my heart. I am asthmatic and keytruda is effecting me to the point of breathlessness whenever I get out of my chair. As long as I am sitting I am fine. I use nebulizer 6-7 times a day and it only acts like a rescue inhaler. My main 3 doctors don't listen to me about how bad it is. I can't go anywhere. It is difficult to explain. It's not like an asthma attack. There is a definite difference.
When I move around ( even slowly) my oxygen levels drop to 84, 85 but as soon as I sit it jumps to 95, 96.
My heart doctor did change one medication but there has been no change in my breathlessness.

I have not heard of anyone else with this problem.
God bless everyone.

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Replies to "I have been on keytruda since 2022 and will have to stay on it every 3..."

@songinmyheart54: it's so difficult to have to deal with multiple diagnoses of cancer and then have to manage side effects of treatment as well.

Shortness of breath has been reported with Keytruda for some individuals. I presume you have been undergoing routine surveillance with imaging after having the metastatic melanoma diagnosis; by this I mean, regular imaging such as CT scans at various intervals to check to see if there has been a recurrence. Most treatment regimens for Keytruda are capped at two years. I'm curious as to the rationale for remaining on Keytruda indefinetily. Have you discussed this with your medical provider?