@debbiehirsch I have CIDP, Chronic Inflammatory Demyelinating Polyneuropathy, or small fiber pn. It shows up for me on all the tests. As for your question, what do you do, there are many things people do for pain relief, and what helps one person may be ineffective for another. Unfortunately, there's no single answer.

I have intense pain in my feet and ankles, and take a few meds to try to make it better. Hizentra is an immuno globulin that I give myself once a week by subcutaneous infusion. I put Lidocaine cream on my feet, mostly at bedtime, to numb the pain so I can go to sleep. I take Tylenol and Meloxicam, but they are more for arthritis. I have experimented with insoles and have them in all my shoes. If bedding causes pain, I have a blanket lifter that makes a tent for my feet. I never walk barefoot! Some people soak their feet in cool water. I discovered that cold, ice water is painful.

All the things I've listed are based on the assumption that you have foot pain. Not everyone has the pain element. Time will tell where your sfpn takes you. I wish you well.

Jim

@debbiehirsch
That would depend on what is causing the SFN. Some SFNs can be treated. There is special testing i.e. autoimmune testing etc. to ascertain whether SFN is idiopathic or is a result of an underlying condition.