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Testosterone Replacement Therapy after 1 year Orgovyx and Radiation?

Posted by ava11 @ava11, Jan 1 11:56am

By March 31st, 2026, it would be 12 months since I stopped Orgovyx and RT. My total Testosterone is 65 now and it was 87 few weeks ago.
My oncologist recommends TRT. But I am reluctant because of the cancer recurrence. He says the risk is same if my T goes up naturally or with TRT, based on new studies.
My main issues are occasional fatigue bouts lasts few seconds and prolonged exercise tolerance and changes in biomarkers.
Any of you have undergone TRT after ADT? What is your experience/
What happened when you stopped TRT. Did your T levels go down?

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chippydoo | @chippydoo | Jan 25 8:46am
In reply to @ava11 "@retireddoc In my case, it is even more confusing because of my age. I don't know..." + (show)
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@retireddoc
In my case, it is even more confusing because of my age. I don't know how much of the low energy and fatigue is from low testosterone of 65 vs just getting older. I don't want to go through TRT and get very little or no improvement!
After I work out in the GYM for an hour with trainer with no problem and try to walk to a restaurant, it is a stop and go with low energy and fatigue. I am assuming that is from low testosterone not my age?

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@ava11 72 here. After a good workout I feel better for hours. Prior to working out I feel like a slug. We are all different I guess.

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mlewelling | @mlewelling | Jan 25 9:49am

I started TRT at 57 years old three months before being diagnosed with PC Gleason (3+4=7) favorable intermediate. TRT Changed my life. The biggest benefit was mental health, anxiety went away, I felt calmer and could think clearer. I was able to put on muscle and weigh is easier to manage. When diagnosed with PC I thought for sure I would be taken off TRT but to my surprise, in all my 5 consultations, all Dr’s agreed I could stay on it. That’s Mayo, UCLA, CA Proton, my urologist and local Oncologist. It helped me tremendously. Of course everyone is different and each our journeys have different twists and turns. It is something to look into though…

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jime51 | @jime51 | Jan 25 12:22pm

This resource may be worth your consideration. It's not a majority opinion or practice yet but offers hope. https://youtu.be/OY9stl6G2nU

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