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I made a decision to stop prolia after multiple years. I had no idea that I would lose the gains while on Prolia but that I would have significant bone loss within months. I began having pain in February 2025 and finally had X-rays in April 2025. There were multiple spinal fractures including acute fractures T 12 and L3. I had kypoplasty in mid June. My posture is bad even after PT and last week I went back to doctor. There is now curvature towards the right side.
I was extremely active before all this happened. It has drastically changed my life. I would never have stopped the drug if I had been informed of the rebound effects. Although I just started Evenity It was interesting to learn that they are manufactured by same company. . I was not informed of the risks associated with stopping the drug. Ask your medical provider questions about all your medications.
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@beachmoma16 Thank you for all of your information and hopefully Evenity will work wonders for you.
@beachmoma16
What I understand is that there is a protocol for discontinuing Prolia after many years taking Prolia. And that is to take one dose infusion of Reclast - to seal in the gains achieved by Prolia- and it must be done on the 6th month date of receiving the next Prolia (which you discontinued). So, if Jan 1, 2026, was your last Prolia injection, the Reclast must be infused on July 1, 2026.
Transitioning from anabolic to anti -resorptive (Evenity > Prolia/Reclast) is generally better supported by guidelines to maintain gains. Not the other way around.
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@beachmoma16 I am so sorry to hear this! Thank you for sharing and I hope you can heal and recover.