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← Return to Tymlos causing belly fat?
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@normahorn I did some research using AI on this and found this possible explanation:
“Hormonal Signaling Crosstalk (Wnt & IGF-1)
Anabolic drugs work by activating growth pathways like Wnt signaling and IGF-1 (Insulin-like Growth Factor 1) to build bone.
Mechanism: These same pathways are active in adipose (fat) tissue. While the drugs are designed to target bone, "off-target" signaling can occasionally promote the maturation of fat cells (adipocytes) in specific areas, such as the abdomen.
Result: This can lead to localized fat storage even if your overall metabolic rate and glucose levels remain stable.”
Replies to "@normahorn I did some research using AI on this and found this possible explanation: “Hormonal Signaling..."
Well, that is bad news. I would have never agreed to go on Forteo if I knew I would end up unhealthy with additional fat tissue. I have gained 8 lbs. and it will not budge despite eating, as always, healthy and exercising. My thyroid numbers are off and my cholesterol numbers have changed.
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@oopsiedaisy Thank you for this explanation, as awful as it is. My understanding is that not everyone has the side effect of abdominal weight gain/bloat.
I wish there were a way to know beforehand how a particular drug may affect other aspects of our body and overall day-to-day health.