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Brinsupri experience after 3+ months

MAC & Bronchiectasis | Last Active: 1 day ago | Replies (44)

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@taracronwall
Brinsupri (brensocatib) works by blocking the enzyme DPP1 (dipeptidyl peptidase 1) to reduce inflammation in non-cystic fibrosis bronchiectasis (NCFB) by stopping neutrophils from activating damaging proteins, leading to fewer lung flare-ups and less lung destruction. It works by preventing the overreaction of these immune cells that cause chronic airway damage.

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@cwal
Thank you for describing the physiology behind that drug. I guess it just blows my mind that it could possibly let prevent flare ups. With my body it’s a virus when I get sick in 2 days Ive got pneumonia thick green can’t breathe. So I’m trying to weigh the side effects with what it would mean in the long run. Will it extend my lung life? Will it actually prevent the quick infections that happen as soon as I get sick? Otherwise when I breathe in someone’s vaping or cigarette smoke or perfume cologne gas exhaust febreeze bathroom scented chemicals at providers offices that usually causes me extra coughing and more time on the vibration vest, reactions to environmental things don’t cause me to have infections only catching a virus. So I’m on the fence. 🧐I’m just glad that there is this forum so we can help one another, grateful!