Not that I know. I have been short of breath and blame it on 2 years of wearing mask for covid. I told my doctor and they had me do a breathing test and said I had no significant change from normal breathing. I use a menthol cough drop if I feel real tight. I do not keep cough drop in till gone as they can be hard on teeth. I use it long enough to free my breathing then I put it back in wrapper. Don't fall asleep with them it can choke you. Also allergies are bad and we have had a dry winter so far. That Don't help either.