@tomrennie
I don’t have significant nausea and diarrhea, except a little diarrhea on occasion. I am taking a pre-emotive nausea pill before the temo.

My problems primarily are severe heartburn., abdominal pain spasms in my colon. I also have fatigue.

My primary care dr given me a regimen for taking anti acid meds throughout the day, as well as anti-spasm med. The meds ok’d by oncologist.

Also, instead of taking temo on empty stomach as specialists at Pham suggested, oncologist told me to eat something before taking temo. And that got rid of middle of the night stomach pain after taking temp.